Zelboraf Uses, Side effects

What is Zelboraf and how to use it?

Zelboraf (vemurafenib) is a kinase inhibitor used to treat metastatic melanoma patients with BRAFV600E mutation that cannot be surgically removed.

What are the side effects of Zelboraf?

Common side effects of Zelboraf include:

    Joint pain,
    tired
    nausea,
    Hair loss
    Skin rash or itching,
    Skin growth (skin label),
    Blurred vision,
    Increase the sensitivity of the eyes to light,
    Hair loss
    Thickened skin,
    Rough scaly spots on the skin,
    Dry skin,
    Skin redness,
    Muscle pain,
    Pain in limbs,
    Backache,
    fatigue,
    Swelling of limbs,
    fever,
    weakness,
    diarrhoea,
    Vomiting
    constipation,
    headache,
    Taste change
    Decreased appetite,
    cough
    sunburn.

description

ZELBORAF (vemurafenib) is a kinase inhibitor, 240 mg for oral tablets.  early access program pharmaceuticals The chemical name of Vemurafenib is propane-1-sulfonic acid {3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro- Phenyl}-amide. Its molecular formula is C23H18ClF2N3O3S and its molecular weight is 489.9. Vemurafenib has the following chemical structure:

Vemurafenib is a white to off-white crystalline solid. It is practically insoluble in aqueous media.

ZELBORAF tablets are for oral administration. Each tablet contains 240 mg of vemurafenib.

The inert ingredients of ZELBORAF are the core of the tablet: hypromellose acetate succinate, croscarmellose sodium, colloidal silica, magnesium stearate and hydroxypropyl cellulose.
Named Patient Program India  Coating: pink and white: polyvinyl alcohol, titanium dioxide, polyethene glycol 3350, talc and iron oxide red.