Friday, July 10, 2020

Abatacept (Orencia) | named patient medicines

Abatacept (Orencia) is usually prescribed after the failure of disease-modifying antirheumatic drugs (DMARD) such as methotrexate but can be used as first-line treatment.

Abatacept is used to reduce inflammation symptoms such as swelling, pain and stiffness. In the long run, it is expected to prevent joint deformities and therefore helps maintain the range of motion.

It is commonly used in patients with moderate to severe rheumatoid arthritis who do not respond to one or more DMARDs (such as methotrexate or other biological drugs). named patient medicines Usually try DMARD first. Abatacept can be used alone or in combination with DMARDs, which makes it more effective, but it cannot be used with other biological drugs (such as TNF inhibitors). Its use in other diseases is still under study.

Unlike some other biological drugs, Abatacept does not block inflammatory proteins such as TNF-α antagonists. Abatacept attaches to the surface of inflammatory cells and blocks communication between these cells. By blocking this communication, Abatacept reduced inflammation.

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