IMATINIB TABLETS VEENAT 400 MG

 

 Introduction

Veenat 400 Tablet belongs to the class of drugs called tyrosine kinase inhibitors. It is used to treat blood cancers (chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors.

Veenat 400 tablets should be taken with food, but it is best to take them at the same time every day for maximum benefit. You should continue taking it as long as your doctor recommends it. The duration of treatment varies according to your needs and response to treatment. Taking the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel these benefits, but unless your doctor tells you, do not stop taking it.

The most common side effects of this drug include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue and abdominal pain. If you experience unexpected rapid weight gain, please tell your doctor. While you are taking this medicine, your doctor may recommend that you regularly monitor blood cells and liver function. If you feel dizzy and blurred vision, do not drive or do anything that requires concentration.

Many other medicines may affect or be affected by this medicine, so please let your medical team know about all medicines you are taking. We do not recommend this medication during pregnancy or breastfeeding. During treatment, it is important for both men and women to use effective contraceptive measures to avoid pregnancy.

USES OF VEENAT TABLET

• Blood Cancer (cronic myeloid leukaemia)
• Blood cancer (Acute lymphocytic leukemia)
• Gastrointestinal stromal tumour 
• Benefits of venata tablets
• 
  
• In blood cancer (chronic myeloid leukemia)
• Blood cancer, also known as leukemia, is a cancer of blood forming tissues that reduces the body's ability to fight infections. Veenat 400 Tablet can kill or prevent the growth of cancer cells, and can also prevent the proliferation of cancer cells. This is an effective and highly toxic drug, and you should discuss the risks and benefits with your doctor. During this treatment, you should avoid drinking alcohol and drink plenty of water to stay hydrated.
• Cancer in the blood (acute lymphocytic leukemia)
• Blood cancer, also known as leukemia, is a cancer of blood forming tissues that reduces the body's ability to fight infections. Veenat 400 Tablet can kill or prevent the growth of cancer cells, and can also prevent the proliferation of cancer cells. This is an effective and highly toxic drug, and you should discuss the risks and benefits with your doctor. During this treatment, you should avoid drinking alcohol and drink plenty of water to stay hydrated.
• In gastrointestinal stromal tumors
• Gastrointestinal stromal tumor (GIST) is the most common type of tumor in the stomach or small intestine. The tumor develops into specialized cells called interstitial cells of Cajal (ICC). Veenat 400 Tablet helps to kill cancer cells and prevent their further growth and spread. Follow the doctor's instructions carefully to get the most benefit.
• 
  
• Side effects of vitamin tablets
• Most side effects do not require any medical care and will disappear as the body adjusts to the medication. If they persist or you are worried about them, please consult your doctor
• Edema (swelling)
• Nausea
• Vomiting
• Muscle cramp
• Musculoskeletal (bone, muscle or joint) pain
• Diarrhea
• Rash
• Fatigue
• Abdominal pain
  
  
• 
  
• How to use VEENAT tablet
  
  
• Take this medicine according to the dosage and duration recommended by your doctor. Swallow whole. Do not chew, crush or break it. Veenat 400 tablets should be taken with food.
• 
  
• How does a VEENAT tablet work?
  
  
• Veenat 400 Tablet is an anti-cancer drug. A protein enzyme, bcr-abl tyrosine kinase, is responsible for the abnormal proliferation of cancer cells. The drug inhibits the proliferation of bcr-abl positive cells (cancer cells) and induces apoptosis (planned cell death). This is how it works to stop or slow the spread of cancer.
  
  
• 
  
• Safety advice
  
  
• alcohol
• Consult your doctor
• It is not known whether it is safe to drink alcohol with Veenat 400 Tablet. Please consult your doctor.
• pregnancy
• Consult your doctor
• Veenat 400 Tablet is not safe to use during pregnancy because there is strong evidence that the developing baby is at risk. However, if the benefits outweigh the potential risks, doctors may rarely prescribe in certain life-threatening situations. Please consult your doctor.
• breast-feeding
• Consult your doctor
• During breastfeeding, Veenat 400 Tablet may be unsafe. Limited human data suggests that the drug may pass into breast milk and harm the baby.
• Breastfeeding women should not breastfeed while using this drug and for one month after stopping the use.
• 
  
• drive
• Insecure Bureau
• Veenat 400 Tablet may cause side effects, which may affect your driving ability.
• kidney
• Patients with kidney disease should use Veenat 400 tablets with caution. The dosage of Veenat 400 Tablet may need to be adjusted. Please consult your doctor.
• liver
• Patients with severe liver disease should use Veenat 400 tablets with caution. The dosage of Veenat 400 Tablet may need to be adjusted. Please consult your doctor.
  
  
• 
  
• What should you do if you forget to take a vitamin tablet?
  
  
• If you miss the dose of Veenat 400 Tablet, skip this step and follow the normal schedule. Do not double the dose.
  
  
• 
  
• Quick tips
  
  
• Always take it with food and a full glass of water to prevent nausea.
• May cause dizziness or blurred vision. Don’t drive or do anything that requires concentration until you know how it will affect you.
• Water retention and swelling are very common side effects of Veenat 400 Tablet. If you have unexpected rapid weight gain, please notify your doctor.
• Do not change the dosage or discontinue use without consulting a doctor.
• Inform the doctor of all the medicines you are taking, including over-the-counter medicines and dietary supplements.
• Your doctor may perform regular blood tests to monitor your liver function and the number of blood cells in your blood.

BORTEZOMIB FOR INJECTION BORTENAT LYOPHILIZED

 Introduction
Bortenat 2mg injection is used to treat multiple myeloma and mantle cell lymphoma. It shows its effect by stopping or slowing the growth of cancer cells.

Bortenat 2mg injection is administered by a qualified medical professional. Your doctor will decide what dosage is needed and how often you need to take it. This will depend on the treatment you receive and may change from time to time. You should take it exactly as recommended by your doctor. Taking the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel these benefits, but unless your doctor tells you, do not stop taking it.

Fatigue, nausea, vomiting and loss of appetite are some of the common side effects of this medicine. It is recommended that you drink plenty of fluids every day during treatment. You should not drive or operate machinery because the medication may cause fatigue and dizziness. This drug can reduce the number of blood cells in the blood (reduce red blood cells and white blood cells), thereby increasing the susceptibility to infection. Regular blood tests are needed to check your blood cells, heart, liver, and blood uric acid levels.

Before taking Bortenat 2mg injection, if you have any liver, kidney, heart disease or bleeding problems, please consult your doctor. If you experience symptoms such as memory loss or difficulty thinking, be sure to consult a doctor. Many other medicines may affect or be affected by this medicine, so please let your medical team know about all medicines you are taking. This medication is not recommended during pregnancy or breastfeeding. During treatment, it is important for both men and women to use effective contraceptive measures to avoid pregnancy.
Uses of Borane Injection
Multiple myeloma
Mantle cell lymphoma

Benefits of Bortidine Injection

In multiple myeloma

If you have multiple myeloma, your body destroys bones faster than they are replaced. This makes the bones weak and painful and breaks more easily. Bortenat 2mg injections and other cancer treatments such as chemotherapy can be prescribed. This is an important part of treatment and can improve the survival rate of patients with multiple myeloma. This drug will kill cancer cells and prevent them from growing further and spreading to other parts of the body. Follow the doctor's instructions carefully to get the most benefit. Calcium and vitamin D3 supplements are also effective. If your blood calcium level is not high, you can prescribe it.

In mantle cell lymphoma

Mantle cell lymphoma is a cancer of the white blood cells in our body, also known as non-Hodgkin's lymphoma. White blood cells are cells that help us fight infection. Bortenat 2mg injection helps limit the growth of cancer and stops the effects of other chemicals needed for cancer growth and further spread. Avoid being in a crowd and wash your hands frequently to prevent infection. Unless your doctor advises otherwise, drink plenty of water.

Side effects of borane injections
Most side effects do not require any medical care and will disappear as the body adjusts to the medication. If they persist or you are worried about them, please consult your doctor
Common side effects of Bortenat
Low platelets
fatigue
Peripheral neuropathy (tingling and numbness of the feet and hands)
Mental illness
nausea
Vomiting
Loss of appetite
fever
Anemia (low number of red blood cells)
diarrhea
Decreased appetite
Decrease in the number of white blood cells (neutropenia)
constipation

How to use borane injection

Your doctor or nurse will give you this medicine. Please don't self-manage.

How does sodium borohydride injection work?

Bortenat 2mg injection is an anticancer drug. It works by preventing or slowing down the breakdown of proteins in cells. As a result, the amount of protein in cancer cells that cause death increases.

Safety advice
alcohol
Insecure Bureau
Bortenat 2mg injection may cause excessive drowsiness and alcohol.
pregnancy
Consult your doctor
It is not safe to use Bortenat 2mg injection during pregnancy because there is strong evidence that the developing baby is at risk. However, if the benefits outweigh the potential risks, doctors may rarely prescribe in certain life-threatening situations. Please consult your doctor.
breast-feeding
Insecure Bureau
It is not safe to use Bortenat 2mg injection during breastfeeding. Data indicates that the drug may be toxic to infants.
drive
Insecure Bureau
Bortenat 2mg injection may cause side effects and may affect your ability to drive.
Bortenat 2mg injection may cause fatigue, dizziness, fainting or blurred vision, thereby affecting your ability to drive.
kidney
Patients with severe kidney disease should use Bortenat 2mg injection with caution. The dosage of Bortenat 2mg injection may need to be adjusted. Please consult your doctor.
There is limited information on the use of Bortenat 2mg injection in these patients.
liver
Patients with liver disease should use Bortenat 2mg injection with caution. The dosage of Bortenat 2mg injection may need to be adjusted. Please consult your doctor.

What should you do if you forget to take bortidine?

If you miss a dose of 2 mg Bortenat injection, please consult your doctor.

Quick tips
Bortenat 2mg injection is a form of intravenous or skin injection under the supervision of a healthcare professional.
Do not skip any doses and complete the course of treatment as recommended by your doctor.
When taking this medication, use effective birth control methods to avoid pregnancy.
During treatment, you may need blood tests to monitor your blood cells, platelet count, liver function, and kidney function.
If you experience a cough, shortness of breath and swelling of your feet, please notify your doctor immediately.

LEDIFOS (LEDIPASVIR 90 MG & SOFOSBUVIR 400 MG TABLETS)

 Introduction

Ledifos 90mg/400mg tablets are a combination of two antiviral drugs. This prescription medicine is used to treat chronic hepatitis C virus (HCV) infection. It fights the virus to resolve the infection.

Ledifos 90mg/400mg tablets should be taken according to the prescribed dose and duration. It can be taken with or without food, but at the same time every day. It is recommended not to consume more than the recommended dose. If you have any health conditions, such as liver or kidney disease, be sure to tell your doctor. Drinking alcohol with this medication is harmful, so it is recommended to limit or avoid drinking alcohol. The course of medication should be completed to achieve better results.

Common side effects of this drug are tiredness and headache. You should drink plenty of water and eat a healthy diet to prevent or overcome side effects. Before taking the medicine, please tell your doctor if you are taking other medicines or supplements.

USES OF LEDIFOS TABLET

Treatment of Chronic hepatitis C virus (HCV) infection

Benefits of LEDIFOS Tablet PC

In the treatment of chronic hepatitis C virus (HCV) infection
Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). When the infection enters a long-term phase, it is called chronic hepatitis C virus infection. Ledifos 90mg / 400mg Tablet helps reduce the amount of hepatitis C virus by preventing the spread of hepatitis C virus in your body. This will help control the infection and help you recover faster. It is important to take the medicine according to the prescription recommended by your doctor.

Side effects of LEDIFOS tablets

Most side effects do not require any medical care and will disappear as the body adjusts to the medication. If they persist or you are worried about them, please consult your doctor

Common side effects of Ledifos
tired
headache

How to use LEDIFOS tablet
Take this medicine according to the dosage and duration recommended by your doctor. Swallow whole. Do not chew, crush or break it. Ledifos 90mg / 400mg tablets can be taken with or without food, but it is best to take it at a fixed time.

How does LEDIFOS tablet work

Ledifos 90mg/400mg tablets are a combination of two antiviral drugs: Ledipasvir and Sofosbuvir. They work by reducing the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Safety advice
alcohol
Consult your doctor
It is not known whether it is safe to drink alcohol with Ledifos 90mg/400mg tablets. Please consult your doctor.
pregnancy
Prescribed safety
Ledifos 90mg/400mg tablets are generally considered safe to use during pregnancy. Animal studies have shown that there is little or no adverse effect on the developing baby. However, human research is limited.
breast-feeding
Prescribed safety
Ledifos 90mg/400mg tablets may be safe during breastfeeding. Limited human data indicate that the drug does not pose any major risks to infants.
drive
Ledifos 90mg/400mg tablets may cause side effects, which may affect your ability to drive.
When Ledifos 90mg/400mg tablets are taken with other drugs used to treat hepatitis C, dizziness and blurred vision may occur, which may affect your driving ability.
kidney
Patients with severe kidney disease should use Ledifos 90mg/400mg tablets with caution. The dosage of Ledifos 90mg/400mg tablets may need to be adjusted. Please consult your doctor.
There is limited information on the use of Ledifos 90mg/400mg tablets in these patients. It is not recommended to adjust the dose for patients with mild to moderate kidney disease.
liver
Prescribed safety
Ledifos 90mg/400mg tablets can be used safely in patients with liver disease. It is recommended not to adjust the dose of Ledifos 90mg/400mg tablets.
Quick tips
Ledifos 90mg/400mg tablets are used to treat chronic hepatitis C virus (HCV) infection.
It is best eaten with daily food.
You usually need to take this medicine every day for 12 or 24 weeks.
Skipping the dose increases the risk of treatment failure. Make sure to take all doses at the right time.
It may cause fatigue, dizziness and blurred vision. Don’t drive or do anything that requires concentration until you know how it will affect you.
Ledifos 90mg/400mg tablets may cause headaches. Drink plenty of water and take suitable painkillers. If it does not disappear, please notify your doctor.
Your doctor may regularly monitor your liver function and the amount of hepatitis C virus in your body.
Don't stop taking this medicine without your doctor's advice.
i

LENALIDOMIDE CAPSULES LENALID 10

 Introduction

Lenalid 10 capsules are used to treat multiple myeloma and lepra reactions. This medicine belongs to a group of medicines that affect the way your immune system works.

Lenalid 10 capsules can be taken with or without food, but try to take them at the same time every day for maximum benefit. Your doctor will decide what dosage is needed and how often you need to take it. This will depend on the treatment you receive and may change from time to time. You should take it exactly as recommended by your doctor. Taking the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel these benefits, but unless your doctor tells you, do not stop taking it.

Some common side effects of this drug include headache, weakness, nausea, rash and dizziness. This medication may reduce the number of blood cells in the blood (reduce red blood cells and white blood cells), thereby increasing susceptibility to infection or bleeding. Therefore, pay more attention to activities that may increase the chance of bleeding or avoid contact with infected patients such as colds. During treatment, regular blood tests are required to check your blood cells.

Many other medicines may affect or be affected by this medicine, so please let your medical team know about all medicines you are taking. This medication is not recommended during pregnancy or breastfeeding. During treatment, it is important for both men and women to use effective contraceptive measures to avoid pregnancy. It is recommended that you drink plenty of water while taking this medicine to stay hydrated.

USES OF LENALID CAPSULE

• Multiple myeloma
• Lepra reaction

Benefits of Reneide capsules

In multiple myeloma

If you have multiple myeloma, your body destroys bones faster than they are replaced. This makes the bones weak and painful and breaks more easily. Lenalid 10 capsules can be prescribed together with other cancer treatments (such as chemotherapy). This is an important part of treatment and can improve the survival rate of patients with multiple myeloma. This drug will kill cancer cells and prevent them from growing further and spreading to other parts of the body. Follow the doctor's instructions carefully to get the most benefit. Calcium and vitamin D3 supplements are also effective. If your blood calcium level is not high, you can prescribe it.

In Lepra reaction

Leprosy is a complex inflammatory reaction that may occur before, during or after leprosy (a serious bacterial skin disease) treatment. These reactions can increase nerve damage and aggravate disability in patients with leprosy. Therefore, lepra reactions need to be treated with drugs such as Lenalid 10 capsules to stimulate the immune system and help recovery. This medication can also prevent further damage caused by the leprosy reaction. Take it as prescribed by your doctor for maximum benefit.

SIDE EFFECTS OF LENALID CAPSULE

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lenalid

• Headache
• Weakness
• Nausea
• Rash
• Dizziness
• Sleepiness
• Edema (swelling)
• Loss of appetite
• Decreased white blood cell count
• Decreased calcium level in blood
• Weight gain
• Muscle weakness
• Fatigue
• Fever
• Anxiety
• Blood clots
• Dry skin
• Weight loss
• Confusion
• Decreased white blood cell count (neutrophils)
• Neuropathy
• Constipation
• Tremor

How to use LENALID capsules

Take this medicine according to the dosage and duration recommended by your doctor. Lenalid 10 capsules can be taken with or without food, but it is best to take it at a fixed time.

How LENALID capsules work

Lenalid 10 capsules are an anti-cancer drug. It works by enhancing the immune system that indirectly attacks cancer cells. It can prevent the growth of new blood vessels in the tumor. It also limits the production of chemical messengers (cytokines and growth factors) that cause cancer cells to grow. This is how it fights cancer.

Safety advice

alcohol

Consult your doctor

It is not known whether it is safe to drink alcohol with Lenalid 10 capsules. Please consult your doctor.

pregnancy

Insecure Bureau

Lenalid 10 capsules are very unsafe to use during pregnancy. After studies on pregnant women and animals have shown significant harmful effects on the developing baby, seek medical advice.

breast-feeding

Consult your doctor

Lenalid 10 capsules may not be safe during breastfeeding. Limited human data suggests that the drug may pass into breast milk and harm the baby.

drive

Insecure Bureau

Lenalid 10 capsules may cause side effects, which may affect your ability to drive.

After taking Lenalid 10 capsules, you may feel dizzy, tired, sleepy, dizzy or blurred vision, which may affect your ability to drive.

kidney

Patients with kidney disease should use Lenalid 10 capsules with caution. The dosage of Lenalid 10 capsules may need to be adjusted. Please consult your doctor.

liver

Patients with liver disease should use Lenalid 10 capsules with caution. The dosage of Lenalid 10 capsules may need to be adjusted. Please consult your doctor.

What should you do if you forget to take LENALID capsules?

If you miss Lenalid 10 capsules, take it as soon as possible. However, if it’s almost time for your next medication, skip the missed medication and go back to the regular schedule. Do not double the dose.

Quick tips

Before and during treatment, you may receive regular blood tests. Lenalidomide may cause a decrease in white blood cells and platelets, which are necessary to fight infection, hemoglobin and blood clotting.

Avoid activities that may cause bruising or injury, and avoid contact with people who have a cold or infection.

It makes your skin sensitive to sunlight. Wear sunscreen or protective clothing when you go out.

May cause dehydration. Drink plenty of water while taking the medicine to stay hydrated.

 Not recommended for use in children and adolescents under 18 years of age.

You should use an appropriate method of contraception before, during, and at least 4 weeks after stopping the medicine.

Women of fertility must undergo pregnancy tests before and after treatment.

Before receiving any medical or dental care, emergency care or surgery, you should inform your doctor or dentist that you are taking Lenalid 10 capsules.

May cause dizziness or drowsiness. Don’t drive or do anything that requires concentration until you know how it will affect you.

During treatment with Lenalid 10 capsules, you may be at risk of developing acute myeloid leukemia, Hodgkin’s lymphoma tumor lysis syndrome, fatal liver problems, severe skin reactions and fatal heart problems. You should discuss the benefits and risks of taking this medicine in advance.

• 
  

IMATINIB TABLETS VEENAT 400 MG

 Introduction

Veenat 400 Tablet belongs to the class of drugs called tyrosine kinase inhibitors. It is used to treat blood cancers (chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors.

Veenat 400 tablets should be taken with food, but it is best to take them at the same time every day for maximum benefit. You should continue taking it as long as your doctor recommends it. The duration of treatment varies according to your needs and response to treatment. Taking the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel these benefits, but unless your doctor tells you, do not stop taking it.

The most common side effects of this drug include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue and abdominal pain. If you experience unexpected rapid weight gain, please tell your doctor. While you are taking this medicine, your doctor may recommend that you regularly monitor blood cells and liver function. If you feel dizzy and blurred vision, do not drive or do anything that requires concentration.

Many other medicines may affect or be affected by this medicine, so please let your medical team know about all medicines you are taking. We do not recommend this medication during pregnancy or breastfeeding. During treatment, it is important for both men and women to use effective contraceptive measures to avoid pregnancy.

USES OF VEENAT TABLET

• Blood Cancer (cronic myeloid leukaemia)
• Blood cancer (Acute lymphocytic leukemia)
• Gastrointestinal stromal tumour 
• Benefits of venata tablets
• In blood cancer (chronic myeloid leukemia)
• Blood cancer, also known as leukemia, is a cancer of blood forming tissues that reduces the body's ability to fight infections. Veenat 400 Tablet can kill or prevent the growth of cancer cells, and can also prevent the proliferation of cancer cells. This is an effective and highly toxic drug, and you should discuss the risks and benefits with your doctor. During this treatment, you should avoid drinking alcohol and drink plenty of water to stay hydrated.
• Cancer in the blood (acute lymphocytic leukemia)
• Blood cancer, also known as leukemia, is a cancer of blood forming tissues that reduces the body's ability to fight infections. Veenat 400 Tablet can kill or prevent the growth of cancer cells, and can also prevent the proliferation of cancer cells. This is an effective and highly toxic drug, and you should discuss the risks and benefits with your doctor. During this treatment, you should avoid drinking alcohol and drink plenty of water to stay hydrated.
• In gastrointestinal stromal tumors
• Gastrointestinal stromal tumor (GIST) is the most common type of tumor in the stomach or small intestine. The tumor develops into specialized cells called interstitial cells of Cajal (ICC). Veenat 400 Tablet helps to kill cancer cells and prevent their further growth and spread. Follow the doctor's instructions carefully to get the most benefit.
• Side effects of vitamin tablets
• Most side effects do not require any medical care and will disappear as the body adjusts to the medication. If they persist or you are worried about them, please consult your doctor
• Edema (swelling)
• Nausea
• Vomiting
• Muscle cramp
• Musculoskeletal (bone, muscle or joint) pain
• Diarrhea
• Rash
• Fatigue
• Abdominal pain
• How to use VEENAT tablet
• Take this medicine according to the dosage and duration recommended by your doctor. Swallow whole. Do not chew, crush or break it. Veenat 400 tablets should be taken with food.
• How does a VEENAT tablet work?
• Veenat 400 Tablet is an anti-cancer drug. A protein enzyme, bcr-abl tyrosine kinase, is responsible for the abnormal proliferation of cancer cells. The drug inhibits the proliferation of bcr-abl positive cells (cancer cells) and induces apoptosis (planned cell death). This is how it works to stop or slow the spread of cancer.
• Safety advice
• alcohol
• Consult your doctor
• It is not known whether it is safe to drink alcohol with Veenat 400 Tablet. Please consult your doctor.
• pregnancy
• Consult your doctor
• Veenat 400 Tablet is not safe to use during pregnancy because there is strong evidence that the developing baby is at risk. However, if the benefits outweigh the potential risks, doctors may rarely prescribe in certain life-threatening situations. Please consult your doctor.
• breast-feeding
• Consult your doctor
• During breastfeeding, Veenat 400 Tablet may be unsafe. Limited human data suggests that the drug may pass into breast milk and harm the baby.
• Breastfeeding women should not breastfeed while using this drug and for one month after stopping the use.
• drive
• Insecure Bureau
• Veenat 400 Tablet may cause side effects, which may affect your driving ability.
• kidney
• Patients with kidney disease should use Veenat 400 tablets with caution. The dosage of Veenat 400 Tablet may need to be adjusted. Please consult your doctor.
• liver
• Patients with severe liver disease should use Veenat 400 tablets with caution. The dosage of Veenat 400 Tablet may need to be adjusted. Please consult your doctor.
• What should you do if you forget to take a vitamin tablet?
• If you miss the dose of Veenat 400 Tablet, skip this step and follow the normal schedule. Do not double the dose.
• Quick tips
• Always take it with food and a full glass of water to prevent nausea.
• May cause dizziness or blurred vision. Don’t drive or do anything that requires concentration until you know how it will affect you.
• Water retention and swelling are very common side effects of Veenat 400 Tablet. If you have unexpected rapid weight gain, please notify your doctor.
• Do not change the dosage or discontinue use without consulting a doctor.
• Inform the doctor of all the medicines you are taking, including over-the-counter medicines and dietary supplements.
• Your doctor may perform regular blood tests to monitor your liver function and the number of blood cells in your blood.

Bendit, Bendamustine Hydrochloride for Injection (Generic version of Treanda)

 What is Treanda? how to use?

Treanda (bendamustine hydrochloride injection) is an antitumor drug (anticancer drug) used to treat chronic lymphocytic leukemia. After unsuccessful treatment of other drugs, Treanda was used to treat indolent B-cell non-Hodgkin's lymphoma.

What are side effects of Treanda?

Common side effects of Treanda include:

• nausea
• vomiting
• diarrhea
• tiredness
• weakness
• mouth sores
• constipation
• upset stomach
• swelling in your hands or feet
• headache
• dizziness
• drowsiness
• loss of appetite
• weight loss
• mild skin rash

Description

Bendamustine hydrochloride is an alkylating agent. The chemical name of bendamustine hydrochloride is 1H-benzimidazole-2-butyric acid, 5-[bis(2-chloroethyl)amino] -1 methyl monohydrochloride. Its empirical formula is C16H21Cl2N3O2·HCl, and its molecular weight is 394.7. Bendamustine hydrochloride contains a methylethylamino group and a benzimidazole heterocyclic ring with a butyric acid substituent, and has the following structural formula:

TREANDA injection (45 mg / 0.5 mL or 180 mg / 2 mL solution)

TREANDA (bendamustine hydrochloride) injection can only be administered intravenously after being diluted with 0.9% sodium chloride injection (USP) or 2.5% glucose/0.45% sodium chloride injection (USP). It is provided in a single-dose vial as a sterile clear, colorless to yellow solution at a concentration of 90 mg/mL bendamustine hydrochloride. Each 0.5 ml vial contains 45 mg of bendamustine hydrochloride, 162 mg of USP propylene glycol and 293 mg of N,N-dimethylacetamide, EP. Each 2 ml vial contains 180 mg of bendamustine hydrochloride, 648 mg of USP propylene glycol and 1172 mg of N,N-dimethylacetamide (EP). Each vial contains 0.2 ml of overfill.

TREANDA for injection (25 mg/vial or 100 mg/vial lyophilized powder)

TREANDA for injection (bendamustine hydrochloride hydrochloride) is only formulated with sterile water for injection (USP), and after injection with 0.9% sodium chloride injection (USP) or 2.5% dextrose/0.45% sodium chloride Intravenous infusion can only be carried out after further dilution of USP. It is provided in a single-dose vial as a sterile, non-pyrogenic white to off-white lyophilized powder. Each 25 mg vial contains 25 mg of bendamustine hydrochloride and 42.5 mg of mannitol, USP. Each 100 mg vial contains 100 mg of bendamustine hydrochloride and 170 mg of mannitol, USP. The pH of the reconstituted solution is 2.5-3.5.

Indications

Chronic Lymphocytic Leukemia (CLL)

TREANDA® is suitable for the treatment of patients with chronic lymphocytic leukemia. The efficacy of first-line therapies other than chlorambucil has not been determined.

Non-Hodgkin's Lymphoma (NHL)

TREANDA is designated for the treatment of patients with indolent B-cell non-Hodgkin lymphoma who have progressed during or within six months of rituximab or rituximab-containing treatment regimens.

Dosage and administration

Select the TREANDA recipe to be managed

There are two formulations of TREANDA, namely solution (TREANDA injection) and lyophilized powder (TREANDA for injection).

If you want to use a closed system transmission device (CSTD), adapter, and syringe containing polycarbonate or acrylonitrile-butadiene-styrene (ABS) before being diluted in an infusion bag, please do not use TREANDA injection [see Preparation for intravenous administration].

If you use a syringe to take out TREANDA injection from the vial and transfer it to an infusion bag, you can only use a polypropylene syringe with a metal needle and polypropylene connector to take out TREANDA injection and transfer it to the infusion bag. The appearance of the polypropylene syringe is translucent.

TREANDA injection and recombinant TREANDA injection have different concentrations of bendamustine hydrochloride. The concentration of bendamustine hydrochloride in the solution was 90 mg/mL, and the concentration of bendamustine hydrochloride in the lyophilized powder reconstituted solution was 5 mg/mL. Do not mix or combine the two formulas.

The TREANDA injection must be withdrawn and transferred to a biological safety cabinet (BSC) or safety isolator for dilution using a polypropylene syringe with a metal needle and a polypropylene needle seat.

If CSTD or adaptor containing polycarbonate or ABS is used as a supplementary protective agent1 before dilution, only TREANDA injection (lyophilized powder formulation) can be used [please refer to the method provided]

Dosage instructions for CLL

Recommended dosage

The recommended dose is 100 mg/m2 administered intravenously within 30 minutes on Day 1 and Day 2 of a 28-day cycle for a maximum of 6 cycles.

Delay in dose of CLL, dose modification and treatment restart

If Grade 4 hematological toxicity or clinically ≥ Grade 2 non-hematological toxicity occurs, the administration of TREANDA should be delayed. Once the non-hematological toxicity returns to ≤1 grade and/or the blood count is improved [absolute neutrophil count (ANC) ≥1 x 109/L, platelet ≥75 x 109/L], TREANDA can be restarted according to the following conditions Attending physician. In addition, the dose may need to be reduced. [See warnings and cautions]

Change the dose of blood toxicity: For toxicity of grade 3 or higher, reduce the dose to 50 mg/m2 on the 1st and 2nd day of each cycle; if toxicity of grade 3 or higher occurs again, in each Decrease the dose to 25 mg/m2 on Day 1 and Day 2 of the cycle.

Dose modification for non-hematological toxicity: For clinically significant grade 3 or higher toxicity, reduce the dose to 50 mg/m2 on the 1st and 2nd day of each cycle.

The attending physician may consider increasing the dose in subsequent cycles as appropriate.

NHL dosage instructions

Recommended dosage

On Days 1 and 2 of the 21-day cycle, the recommended intravenous dose is 120 mg/m2 within 60 minutes for a maximum of 8 cycles.

NHL dose delay, dose modification and treatment restart

If Grade 4 hematological toxicity or clinically ≥ Grade 2 non-hematological toxicity occurs, the administration of TREANDA should be delayed. Once the non-hematological toxicity returns to ≤1 grade and/or the blood count is improved [absolute neutrophil count (ANC) ≥1 x 109/L, platelet ≥75 x 109/L], TREANDA can be restarted according to the following conditions Attending physician. In addition, the dose may need to be reduced. [See warnings and cautions]

Change the dose of hematological toxicity: For grade 4 toxicity, reduce the dose to 90 mg/m2 on the 1st and 2nd day of each cycle; if grade 4 toxicity occurs again, on the 1st and the first day of each cycle Reduce the dose to 60 mg/m2 in 2 days.

Dose adjustment for non-hematological toxicity: For toxicity of grade 3 or higher, reduce the dose to 90 mg/m2 on the 1st and 2nd day of each cycle; if toxicity of grade 3 or higher recurs, then Reduce the dose to 60 mg/m2 on Day 1 and Day 2 of each cycle.

Preparation for intravenous administration

TREANDA is a cytotoxic drug. Please follow applicable special handling and disposal procedures.

TREANDA injection (45 mg / 0.5 mL or 180 mg / 2 mL solution)

TREANDA Injection must be diluted in a biological safety cabinet (BSC) or isolator.

When preparing the concentrated TREANDA injection and transferring it to the infusion bag, do not use equipment containing polycarbonate or ABS. However, after diluting TREANDA Injection into an infusion bag, devices containing polycarbonate or ABS can be used, including infusion sets.

TREANDA injection contains N,N-dimethylacetamide (DMA) and is not compatible with devices containing polycarbonate or ABS. It has been shown that devices containing polycarbonate or ABS (including CSTD, adapters and syringes) will dissolve when in contact with DMA present in the product. This incompatibility can lead to equipment failure (such as CSTD component leakage, damage or operational failure), possible product contamination, and potentially serious adverse health consequences for practitioners, including skin reactions; or for patients, including but not limited to if Small blood vessels receiving products contaminated with dissolved ABS or polycarbonate may cause blockage of small blood vessels. Equipment compatible with diluted TREANDA injection can be provided.

If you use a syringe to take out TREANDA injection from the vial and transfer it to an infusion bag, you can only use a polypropylene syringe with a metal needle and polypropylene connector to take out TREANDA injection and transfer it to the infusion bag.

Each bottle of TREANDA injection can only be used in a single dose.

Using a polypropylene syringe with a metal needle and a polypropylene sleeve, aseptically extract the volume required for the required dose from the 90 mg/mL solution.

Immediately transfer the solution to a 500 mL 0.9% sodium chloride injection USP (normal saline) infusion bag. As an alternative to 0.9% sodium chloride injection USP (normal saline), 500 mL 2.5% glucose/0.45% sodium chloride injection USP infusion bag can be considered. The final final concentration of bendamustine hydrochloride in the infusion bag should be within 0.2 – 0.7 mg/mL.

After diluting TREANDA Injection into an infusion bag, you can use equipment containing polycarbonate or ABS, including an infusion set.

Before administration, visually inspect the filled syringe and the prepared infusion bag to ensure that there are no visible particles. The admixture should be a colorless to yellow transparent solution

As mentioned above, use 0.9% sodium chloride injection (USP) or 2.5% glucose/0.45% sodium chloride injection (USP) for dilution. No other thinners have proven to be compatible.

If you want to use a closed system transmission device or an adapter containing polycarbonate or ABS as supplementary protection during the preparation process, please use only TREANDA injections (lyophilized formulations).

Each vial of TREANDA injection can only be used in a single dose.

Reconstitute each TREANDA injection vial aseptically as follows:

25 mg TREANDA vial for injection: add only 5 mL sterile water for injection, USP.

TREANDA 100 mg vial for injection: add only 20 mL of sterile water for injection, USP.

Shake thoroughly to obtain a transparent, colorless to light yellow solution with a concentration of 5 mg/mL bendamustine hydrochloride. The lyophilized powder should be completely dissolved within 5 minutes. The reconstituted solution must be transferred to the infusion bag within 30 minutes after reconstitution. If particulate matter is observed, recycled products must not be used.

Aseptically draw the required volume of the required dose (based on a concentration of 5 mg/mL), and then immediately transfer it to a 500 mL 0.9% sodium chloride injection USP (normal saline) infusion bag. As an alternative to 0.9% sodium chloride injection USP (normal saline), 500 mL 2.5% glucose/0.45% sodium chloride injection USP infusion bag can be considered. The final final concentration of bendamustine hydrochloride in the infusion bag should be within 0.2 – 0.6 mg/mL. After transferring, mix the contents of the infusion bag thoroughly.

Before administration, visually inspect the filled syringe and the prepared infusion bag to ensure that there are no visible particles. The mixture should be a transparent colorless to light yellow solution.

As mentioned above, use sterile water for injection (USP) for preparation, and then use 0.9% sodium chloride injection (USP) or 2.5% glucose/0.45% sodium chloride injection (USP) for dilution, as described above. No other thinners have proven to be compatible.

General information

When the solution and container permit, the parenteral drug should be visually inspected for particulate matter and discoloration before administration. Any unused solution should be discarded in accordance with the institutional procedures for anti-tumor drugs.

MELPHALAN (ALKERAN)

Mefalan

Chemocare.com uses generic names in all drug instructions. Megace Alkeran is the trade name of Melphalan. L-PAM and L-Sarcolysin and phenylalanine mustard are other names for Melphalan. In some cases, when referring to the generic drug name melphalan, healthcare professionals may use the trade name megace alkeran or other names L-PAM or L-Sarcolysin or phenylalanine mustard.

Type of drug: Melphalan is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. The drug is classified as an "alkylating agent." (For more details, see the "Effects of this drug" section below).

what mefalan is used for:

• Multiple myeloma
• Ovarian cancer
• Neuroblastoma
• Rhabdomyosarcoma 
• Breast cancer
• Used in some conditioning regimens prior to bone marrow transplant

How to give Melphalan:

Such as oral medicine. The size of the tablet is 2 mg.

Take the medicine on an empty stomach (1 hour before meals to 2 hours after meals).

As an intravenous injection or infusion (intravenous, intravenous injection).

The amount of melphalan you will receive depends on many factors, including height and weight, general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dosage and schedule.

side effect:

Important things to remember about the side effects of melphalan:

Most people do not experience all the side effects listed.

The onset and duration of side effects are usually predictable.

The side effects are almost always reversible and will disappear after the treatment is completed.

There are many options to help minimize or prevent side effects.

There is no relationship between the existence or severity of side effects and the effectiveness of the drug.

The side effects of melphalan and their severity depend on the amount of drug used. In other words, high doses may have more serious side effects.

The following side effects are common in patients taking melphalan (incidence rate is more than 30%):

Low blood count. Your white and red blood cells and platelets may decrease temporarily. This can increase your risk of infection, anemia and/or bleeding. This impact may prolong and accumulate.

Nausea and vomiting. (Slight regular medication, high-dose treatment may aggravate the condition)

These side effects are less common in patients receiving melphalan (approximately 10-29%):

Allergic reactions (the pill form is rare, and it occurs in about 10% of patients in the intravenous form).

Oral ulcers (mild by regular medication, but high-dose treatment may be severe).

Diarrhea (light regular medication, high-dose treatment may aggravate diarrhea).

Loss of fertility. This means that your fertility or fertility may be affected by Melphalan. Discuss this issue with your healthcare provider.

Alopecia (regular administration is rare, usually in high-dose administration for bone marrow transplantation).

Nephrotoxicity (see kidney problems): Conventional doses are not common and are seen when melphalan is taken in high doses for bone marrow transplantation.

Arrhythmia (see Heart Problems): Conventional doses are not common, and are seen when melphalan is taken in high doses for bone marrow transplantation.

Precaution:

Before starting melphalan treatment, make sure you tell your doctor about other medicines you are taking (including prescription drugs, over-the-counter drugs, vitamins, herbal medicines, etc.). Unless specifically permitted by your doctor, do not take aspirin or products containing aspirin.

When taking melphalan, do not receive any form of immunization without the permission of your doctor.

If you are pregnant or may be pregnant, please inform your healthcare professional before starting this treatment. Pregnancy category D (Melphalan may be harmful to the fetus. Women who are pregnant or about to become pregnant must be informed of the potential harm to the fetus).

For men and women: Do not become pregnant (pregnant) while taking melphalan. It is recommended to use contraceptive methods such as condoms. Discuss with your doctor when it is safe to get pregnant or get pregnant after treatment.

Do not breastfeed while taking this medication.

Self-care tips:

If taking Melphalan Pills, please take them on an empty stomach 1 hour before or 2 hours after meals.

Unless otherwise stated, drink at least 2 to 3 quarts of liquid every 24 hours.

You may be at risk of infection, so please try to avoid crowds or people with colds and people who feel unwell, and immediately report fever or any other signs of infection to the medical staff.

Wash your hands often.

To help treat/prevent mouth ulcers, please use a soft toothbrush and rinse with 1/2 to 1 teaspoon of baking soda and/or 1/2 to 1 teaspoon of salt mixed with 8 ounces of water 3 times a day.

Use an electric razor and a soft toothbrush to minimize bleeding.

Avoid contact sports or activities that may cause injury.

This medicine hardly causes nausea when taken in pill form. However, if you feel nauseous, take anti-nausea medications as prescribed by your doctor and eat small and frequent meals. Inhalation of lozenges and chewing gum may also help.

Avoid direct sunlight. Wear SPF 15 (or higher) sunscreen and protective clothing.

In general, the intake of alcoholic beverages should be kept to a minimum or avoided altogether. You should discuss this with your doctor.

Get plenty of rest.

Maintain good nutrition.

If you experience symptoms or side effects, be sure to discuss with your medical team. They can prescribe medication and/or provide other effective solutions to such problems.

How Melphalan works:

Cancerous tumors are characterized by cell division, which is no longer controlled as in normal tissues. When "normal" cells come into contact with similar cells, they stop dividing. This mechanism is called contact inhibition. Cancer cells lose this ability. Cancer cells no longer have the normal inspection and balance to control and limit cell division. Whether it is a normal cell or a cancer cell, the process of cell division is carried out through the cell cycle. The cell cycle goes from the quiescent phase to the active growth phase, and then to mitosis (division).

The ability of chemotherapy to kill cancer cells depends on its ability to prevent cell division. Usually, these drugs work by destroying RNA or DNA that tells cells how to replicate themselves during division. If cells cannot divide, they will die. The faster a cell divides, the more likely it is that chemotherapy will kill the cell, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis).

Chemotherapy drugs that affect cells only when they divide are called cell cycle specificity. Chemotherapy drugs that affect cells in a resting state are called non-cell cycle-specific cell cycles. Set the schedule of chemotherapy based on the cell type, the rate of cell division, and how long a given drug may be effective. This is why chemotherapy is usually performed in cycles.

Chemotherapy is most effective in killing rapidly dividing cells. Unfortunately, chemotherapy does not know the difference between cancer cells and normal cells. "Normal" cells will re-grow and stay healthy, but at the same time, side effects will occur. The "normal" cells most commonly affected by chemotherapy are blood cells, cells in the mouth, stomach and intestines, and hair follicles. Causes low blood counts, mouth sores, nausea, diarrhea and/or hair loss. Different drugs may affect different parts of the body.

Melphalan is classified as an alkylating agent. Alkylating agents are most active during the quiescent phase of the cell. These drugs are cell cycle non-specific. There are several types of alkylating agents:

Mustard gas derivatives: Mechlorethamine, Cyclophosphamide, Chlorambucil, Melphalan, and Ifosfamide.

Ethylenimines: Thiotepa and Hexamethylmelamine.

Alkylsulfonates: Busulfan.

Hydrazines and Triazines: Altretamine, Procarbazine, Dacarbazine and Temozolomide.

Nitrosureas: Carmustine, Lomustine and Streptozocin. Nitrosureas are unique because, unlike most chemotherapy, they can cross the blood-brain barrier. They can be useful in treating brain tumors.

Metal salts: Carboplatin, Cisplatin, and Oxaliplatin.

METFORMIN-TAB

Metformin can be used with a proper diet and exercise plan, and may be used with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs and sexual function problems. Proper control of diabetes can also reduce the risk of heart attack or stroke. The role of metformin is to help restore the body's proper response to naturally-produced insulin. It also reduces the amount of sugar produced by the liver and the amount of sugar absorbed by the stomach/intestines.

How to use metformin orally

Please read the "Patient Information Booklet" provided by your pharmacist before starting to take metformin and every time you supplement it. If you have any questions, please consult your doctor or pharmacist.

Follow your doctor’s instructions to take this medication by mouth, usually with meals 1-3 times a day. Unless your doctor instructs otherwise, drink plenty of fluids while taking this medicine.

The dosage depends on your medical condition, response to treatment, and other medications you may be taking. Be sure to inform your doctor and pharmacist of all products you use (including prescription drugs, over-the-counter drugs, and herbal products). To reduce the risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and then gradually increase the dose. Follow the doctor's instructions carefully.

Take this medicine regularly to get the most benefit from it. Remember to use it at the same time every day.

If you are already taking another diabetes medication (such as chlorpropamide), follow your doctor's instructions carefully to stop/continue using the old medication and start using metformin.

Check blood sugar regularly as directed by your doctor. Follow up the results and share with your doctor. Tell the doctor that your blood glucose measurement is too high or too low. Your dosage/treatment may need to be changed.

TRULICITY, DULAGLUTIDE INJECTION SIDE EFFECTS

 There may be nausea, diarrhea, vomiting, abdominal pain, upset stomach, decreased appetite, tiredness or weakness. If any of these effects persist or worsen, tell your doctor or pharmacist immediately.

Remember, your doctor prescribed this medicine because he or she judged that the benefits to you outweigh the risks of side effects. Many people who use this drug do not have serious side effects.

If you have any serious side effects Because Trulicity, please tell your doctor immediately, including: slow/irregular heartbeat, signs of kidney problems (such as changes in urine output), changes in vision.

Constant vomiting/diarrhea can cause severe body water loss (dehydration) and kidney problems. If you notice any symptoms of dehydration, such as abnormally reduced urination, dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness, please contact your doctor immediately.

If you have any very serious side effects, seek medical help immediately, including: signs of pancreatitis (such as persistent nausea/vomiting, severe stomach/abdominal/back pain).

Although duraglutide by itself does not usually cause hypoglycemia (hypoglycemia), if this drug is prescribed with other diabetes medications, hypoglycemia may occur. Discuss with your doctor or pharmacist whether you need to lower the dose of other diabetes medications. Drinking a lot of alcohol, not getting enough calories from food or engaging in unusually strenuous exercise can also cause hypoglycemia. Symptoms may include sudden sweating, trembling, rapid heartbeat, hunger, blurred vision, dizziness, or tingling of hands/foot. It is a good habit to carry glucose tablets or gels to treat hypoglycemia. If you do not have these reliable forms of glucose, please use instant sugar (such as table sugar, honey or candy) or drink fruit juice or non-edible soda to raise blood sugar quickly. Tell your doctor immediately about the reaction and use of the product. To help prevent hypoglycemia, eat regularly and don’t skip meals. Contact your doctor or pharmacist to find out what to do if you miss a meal.

Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, shortness of breath and fruity breath odor. If these symptoms occur, please tell your doctor immediately. Your dose may need to be increased.

Very severe allergic reactions to this drug are rare. However, if you notice any symptoms of a severe allergic reaction, including skin rash, itching/swelling (especially face/tongue/throat), severe dizziness, and difficulty breathing, please seek medical help immediately.

This is not a complete list of possible side effects. If you notice other effects not listed above, please contact your doctor or pharmacist.

TRULICITY, DULAGLUTIDE INJECTION USES

 How to use Trulicity Pen Injector.

Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using dulaglutide and each time you get a Trulicity. If you have any questions, ask your doctor or pharmacist.

Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin.

Inject this medication under the skin in the thigh, abdomen, or upper arm as directed by your doctor, usually once every 7 days. Do not inject into a vein or muscle. It may be used with or without meals.

If you are also using insulin, give dulaglutide and insulin as separate injections. Do not mix them. You may inject these medications in the same area of the body, but the injection sites should not be next to each other.

Do not share your pen device with another person, even if the needle is changed. You may give other people a serious infection, or get a serious infection from them. Learn how to store and discard medical supplies safely.

Use this medication regularly to get the most benefit from it. To help you remember, use it on the same day each week. It may help to mark your calendar with a reminder. Carefully follow the medication treatment plan, meal plan, and exercise program your doctor has recommended.

The dosage is based on your medical condition and response to treatment. Your doctor will start you on a low dose first to decrease your risk of stomach/abdominal side effects, and gradually increase your dose. Follow your doctor's instructions carefully.

Tell your doctor if your condition does not improve or if it worsens (such as if your blood sugar remains high or increases).