Lonsurf

 Generic Name: Trifluridine/Tipiricil

Trifluridine/tipiricil is the generic name for the trade name drug, Lonsurf. In some cases, health care professionals may use the trade name, Lonsurf, when referring to the generic drug name, trifluridine/tipiricil.

Drug Type: Trifluridine/tipiricil is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. pharma consulting companies,This medication is classified as an antimetabolite/pyrimidine analog; antimetabolite/thymidine phosphorylase inhibitor. (For more detail, see "How Trifluridine/tipiricil Works" below).

What Trifluridine/tipiricil Is Used For:

• Trifluridine/tipiricil is used to treat metastatic colorectal cancer in patients who have previously been treated with fluoropyrimidine, oxaliplatin, and irinotecan based chemotherapy, an anti-VEGF biological therapy, and an anti-EGFR therapy (if RAS wild type).
• To treat metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma previously treated with at least two prior lines of chemotherapy that included fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu-targeted therapy.

Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.

How Trifluridine/tipiricil Is Given:

• Trifluridine/tipiricil is a tablet that is taken by mouth.
• Take twice a day within one hour of eating your morning and evening meals.
• Take with a glass of water.
• The tablets come in two strengths and you may need to take a combination of the two strengths to get to your specific dose. Follow your instructions carefully.
• Trifluridine/tipiricil is usually taken twice a day on days 1 to 5, and days 8 to 12 of a 28 day cycle.

The amount of trifluridine/tipiricil that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have. Your doctor will determine your exact dosage and schedule.