Thursday, April 23, 2020

Kazano (Alogliptin and Metformin HCl Tablets): Uses, Dosage ...

Alogliptin and metformin are oral diabetes drugs that help control blood sugar levels. The role of metformin is to reduce the production of glucose (sugar) in the liver and reduce the absorption of glucose by the intestine.





METFORMIN is a combination of 2 drugs used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.






The combination of alogliptin and metformin can be used alone or in combination with other drugs, combined with appropriate diet and exercise to treat the high blood sugar levels caused by type 2 diabetes. Alogliptin can help control blood sugar levels by increasing substances in the body that cause the pancreas to release more insulin. When there is too much sugar in the blood, it also sends a signal informing the liver to stop producing sugar (glucose). Metformin reduces the absorption of sugar in the stomach, reduces the release of sugar stored in the liver, and helps your body make better use of sugar. The drug cannot help patients with insulin dependence or type 1 diabetes.

This medicine can only be used under a doctor's prescription.

Proper Use

Follow the special diet plan given to you by your doctor carefully. This is the most important part of controlling diabetes, and it is necessary if the medicine works properly. Exercise regularly and test the sugar in the blood or urine as instructed.

This medicine should be accompanied by the "Guide to Medication." Please read and follow these instructions carefully. Ask your doctor if you have any questions.

Swallow the entire tablet. Don't crush, crush or chew it. Take this medicine with food.

Dosage

For different patients, the dose of this drug will be different. Follow the doctor's order or the instructions on the label. The information below includes only the average dose of the drug. If your dosage is different, do not change it unless your doctor tells you.

The amount of medicine you take depends on the strength of the medicine. Similarly, the number of doses taken each day, the time allowed between two doses, and the length of time the drug is taken depends on the medical problem you are using.

For oral dosage forms (tablets):

     For type 2 diabetes:

  •  Adults-First, take 2 tablets 1 tablet per day (agliptin 12.5 mg [mg] plus metformin 500 mg or alogliptin 12.5 mg plus metformin 1000 mg). Your doctor may adjust your dosage as needed. However, the daily dose usually does not exceed 25 mg of alogliptin plus 2000 mg of metformin.
  • Children-usage and dosage must be determined by a doctor.

Missed Dose

If you miss the dose of this medicine, please take it as soon as possible. However, if your next dose is approaching, skip the missed dose and return to the regular dosing schedule. Do not double the dose.

Use & Storage


Store the medicine in a closed container at room temperature, away from heat, moisture and direct light. Avoid freezing.

Keep out of the reach of children.

Do not keep outdated medicines or medicines that are no longer needed.

Ask your health care professional how you should dispose of any medicines you don't use.

Before Using

When deciding to use a drug, one must weigh the risks of taking the drug and the benefits it can bring. This is a decision that you and your doctor will make. For this drug, the following points should be considered:

Allergy

Tell your doctor if you have had any abnormal or allergic reactions to this medicine or any other medicine. If you have other types of allergies, such as food, dyes, preservatives or animals, please also inform your healthcare professional. For non-prescription products, please read the label or packaging ingredients carefully.

Pediatrics

In the pediatric population, the effect of age on combined treatment with alogliptin and metformin has not been properly studied. Safety and effectiveness have not been determined.

Breast-feeding

Women do not have enough research to determine the risk of infants using this drug during breastfeeding. Before taking this medication during breastfeeding, weigh the potential benefits against the potential risks.

Precaution

It is very important that your doctor check your condition regularly to ensure that the medicine works properly and decide whether to continue taking it. Blood and urine tests may be required to check for adverse effects.

If symptoms of lactic acidosis occur, emergency medical help should be obtained immediately.

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